Common mechanism of renin angiotensin system and nuclear factor-kappa B in acute pancreatitis

VernacularTitle:肾素-血管紧张素系统及核因子-κB在急性胰腺炎中的共同作用
Author: Yucen WU
Publication Type:Journal Article
Keywords: Acute pancreatitis; Renin angiotensin system; NF-κB; Inflammation reaction
From: Chinese Journal of Emergency Medicine 2016;25(1):116-121
CountryChina
Language:Chinese
Abstract: Objective Acute pancreatitis (AP) is a common acute abdomen which is widely discussed by scientists for its fast onset,acute progress and accompanied complications including SIRS and MODS.Although the therapeutic efficacy of AP was improved with the improvements in critical care,the incidence and mortality of AP remains high worldwide.The precise mechanism of AP is complicated and still controversial up to now.Recently,the regulatory mechanism of renin angiotensin system (RAS) and nuclear factor-kappa B (NF-κB) on AP has drawn attention of people.And the research could provide crucially important theoretical basis for clinical treatment.In this article,the latest research about the connection among RAS,NF-κB and AP were reviewed.