Clinical Observation of Modified Yanghe Decoction Combined with Analgesic Western Medicine in Relieving Cancerous Pain of Osseous Metastasis Patients
10.13359/j.cnki.gzxbtcm.2015.03.006
- VernacularTitle:阳和汤加减联合西医止痛药治疗骨转移癌疼痛的临床观察
- Author:
Yunfang ZHANG
;
Ming ZHANG
;
Yingjin FU
- Publication Type:Journal Article
- Keywords:
Yanghe Decoction;
Oxycodone hydrochloride;
Osseous metastasis cancer;
Cancerous pain
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2015;(3):410-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of modified Yanghe Decoction combined with analgesic western medicine on relieving cancerous pain and constipation and on improving the quality of life ( QOL) of osseous metastasis patients. Methods A total of 200 patients with cancerous pain were evenly randomized into treatment group and control group in the admission order. The control group was given oral use of oxycodone hydrochloride controlled-release tablets, and the treatment group was given modified Yanghe Decoction on the basis of treatment for the control group. Twenty-one days constituted one treatment course. After one treatment course, the effect on relieving pain and constipation and on improving QOL were evaluated in both groups. Results (1) The analgesic efficiency was 95.0 % in the treatment group, and was 81.0 % in the control group, the analgesic efficiency of the treatment group was better than that of the control group ( P<0.05) . ( 2) Constipation occurred in 92 cases of the treatment group and was relieved to various degrees in 88 cases after treatment, with an efficiency of 95.7%. In the control group, constipation occurred in 91 cases, but was not relieved after treatment. The treatment group had better effect on relieving constipation than the control group (P<0.05) . (3) The total effective rate on improving QOL was 89.0% in the treatment group and was 71.0% in the control group, the difference being significant (P<0.05) . (4) Both groups had 2 cases of drug-induced mild hepatic damage, and the damage disappeared after symptomatic treatment . Conclusion Modified Yanghe Decoction combined with analgesic western medicine shows good toxicity-reducing and efficiency-enhancing effect for the treatment of cancerous pain.
