Therapeutic Effect of Arthroscopic Debridement Plus Oral Use of Chinese Medicine for Knee Osteoarthritis in Early and Middle Stage
10.13359/j.cnki.gzxbtcm.2014.06.010
- VernacularTitle:关节镜清理术结合中药治疗早中期膝关节骨性关节炎的疗效研究
- Author:
Limin CAI
;
Zhichao TAN
;
Binshan ZHANG
;
Shengchao YUAN
;
Shuyang XIAO
- Publication Type:Journal Article
- Keywords:
Knee Osteoarthritis/TCM-WM therapy;
Guanjietong Tablets/therapeutic use;
Arthroscopic debridement
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2014;(6):898-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of arthroscopic debridement combined with oral use of Chinese medicine Guanjietong Tablets ( GT) for knee osteoarthritis in the early and middle stage. Methods Ninety knee osteoarthritis patients in the early and middle stage were evenly randomized into three groups, namely GT group, glucosamine sulfate group and blank control group. All of the three groups received arthroscopic debridement, and additionally, GT group and glucosamine sulfate group were given the corresponding medicine orally. We observed Lysholm knee scores of the three groups before operation, and 2 weeks, 3 months and one year after operation, and compared the knee joint space before operation and one year after operation showed by digital X-ray photograpy. Results ( 1) Lysholm knee scores in the three groups were increased 2 weeks, 3 months and one year after operation when compared with those before operation, the difference being significant (P<0.05) . Three months and one year after operation, the scores of GT group and glucosamine sulfate group differed from those of the blank control group (P<0.01). One year after operation, the scores of GT group differed from those of glucosamine sulfate group ( P<0.05). ( 2) The results of knee joint space showed by digital X-ray photography at knee position of weight loading indicated that the difference was insignificant between GT group and glucosamine sulfate group one year after operation ( P> 0.05) , but the difference between the two groups and the blank control group was significant (P<0.05). The difference of knee joint space was insignificant before operation and one year after operation in GT group and glucosamine sulfate group ( P>0.05) , while was significant in the blank control group ( P<0.05). Conclusion Arthroscopic debridement alone has certain short-term curative effect in treating knee osteoarthritis in the early and middle stage, but the effect will decline with the extension of time. Arthroscopic debridement combined with Guanjietong Tablets could delay the narrowing of joint space and maintain the clinical curative effect, which will delay the time for artificial joint replacement.
