Research progress of Luminal B breast cancer
10.3760/cma.j.issn.1006-9801.2015.12.022
- VernacularTitle:管腔B型乳腺癌的研究进展
- Author:
Bingchao QI
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Luminal B subtype;
Endocrine therapy;
Targeted therapy
- From:
Cancer Research and Clinic
2015;27(12):857-861
- CountryChina
- Language:Chinese
-
Abstract:
Luminal B breast cancer is a main subtype of breast cancer.Disease free survival and overall survival rate of patients with Luminal B subtype are lower than those of patients with Luminal A subtype.Luminal B breast cancer is often treated with chemotherapy and endocrine therapy,and anti-Her-2 therapy is also essential for Luminal B/Her-2 positive breast cancer,but the prognosis is still poor.With the increasing understanding of Luminal B breast cancer,new targets are developed and used for improving treatment effect.This review will describe the clinical and pathological features,factors affecting prognostic,common treatments and new therapeutic targets for Luminal B breast cancer.
