Advances in the effect of miRNA on regulating lung development
10.3760/cma.j.issn.1673-4408.2016.03.003
- VernacularTitle:microRNA 调控肺发育的研究进展
- Author:
Yujiao XING
;
Xindong XUE
;
Jianhua FU
- Publication Type:Journal Article
- Keywords:
miRNA;
Lung development;
Microarray;
Bronchopulmonary dysplasia
- From:
International Journal of Pediatrics
2016;43(3):173-176
- CountryChina
- Language:Chinese
-
Abstract:
miRNAs are a group of 22 ~25 nucleotides endogenous non-coding RNAs,which regulate gene expression at the post-transcription level by cause the degradation or translational suppression of target mR-NAs.In recent years,studies have demonstrated that miRNAs widely participate in cell differentiation,prolifera-tion,organ development and lipid metabolism,and are closely related to the formation of many kinds of diseases. The biological function of miRNAs and their effects on regulating prenatal and postnatal lung development are reviewed in this paper.
