DNA methylation and asthma
10.3760/cma.j.issn.1673-4408.2016.03.004
- VernacularTitle:DNA 甲基化与支气管哮喘
- Author:
Simin SUN
;
Hongmei QIAO
- Publication Type:Journal Article
- Keywords:
Asthma;
T cell;
Epigenetics;
DNA methylation
- From:
International Journal of Pediatrics
2016;43(3):177-179
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma,a complex genetic disease,is influenced by environmental factors.As a connection of genetic susceptibility factors and environmental factors,the role of epigenetics in the pathogenesis of bronchial asthma is attracting more attention.DNA methylation,the most common form of epigenetic modifi-cations,can be influenced by the environment and dietary factors,thereby have an effect on the differentiation of CD4 +T lymphocyte,promoting the development of asthma.
