Progress in the mechanism and treatment of coronary artery thrombosis caused by Kawasaki disease
10.3760/cma.j.issn.1673-4408.2016.03.013
- VernacularTitle:川崎病冠状动脉血栓形成发病机制及治疗进展
- Author:
Qiuyue LIANG
;
Xiaoyan LIU
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Thrombosis;
Endothelial cell;
Treatment
- From:
International Journal of Pediatrics
2016;43(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
The mechanism of coronary artery thrombosis(CAT)caused by Kawasaki disease is not clear yet.Endothelial injury,hypercoagulability and hemodynamic change of coronary arteries are now considered as the main causes in recent studies.As The clinical symptom of acute thrombus caused by Kawasaki disease is un-conspicuous,cardiac ultrasound should be use actively and thrombolytic therapy should be performed within 12 hours after thrombus formation or the onset of acute myocardial infarction.Intervention or intravenous thrombol-ysis are both proved to be effective.Treatment with oral antitplatelet drugs,such as aspirin,combine with warfa-rin is suggested to relieve acute myocardial infarction in the chronic phase.The adverse reactions of antithrom-botic and anticoagulant drugs should be monitored though they are minor.
