Biomarkers of preterm infant low birth weight brain damage
10.3760/cma.j.issn.1673-4408.2016.03.018
- VernacularTitle:早产儿脑损伤的相关生物学标志物
- Author:
Juan TANG
;
Shan CHEN
;
Wei ZHOU
- Publication Type:Journal Article
- Keywords:
Brain damage;
Markers;
Biology;
Preterm infant;
Low birth weight
- From:
International Journal of Pediatrics
2016;43(3):234-238
- CountryChina
- Language:Chinese
-
Abstract:
Along with contemporary development of life support technology in perinatology and neo-natal intensive care,mortality of preterm infants has been reduced.However,the problems caused by the brain damage have been attracting more and more attention.The long-term outcome of prematures depends on their nervous system sequelae among the total complications.Preterm infants'brain damage mainly includes intravent-ricular hemorrhage(IVH)and periventricular leukomalacia(PVL).IVH and its complications are the main causes of early death,mental and physical developmental disorder of neonatals.Thus,the early diagnosis of brain dam-age,especially PVL,has become a serious problem that we are going to face.The scholars in or aboard hao payed close attention to these markers,such as MBP、S100B、ACT A、NF-L、NGB、MMP、IL-6、IL-10、IL-1 1 、NSE.The paper reviews these biological markers.