Biomarkers of preterm infant low birth weight brain damage

VernacularTitle:早产儿脑损伤的相关生物学标志物
Author: Juan TANG ; Shan CHEN ; Wei ZHOU
Publication Type:Journal Article
Keywords: Brain damage; Markers; Biology; Preterm infant; Low birth weight
From: International Journal of Pediatrics 2016;43(3):234-238
CountryChina
Language:Chinese
Abstract: Along with contemporary development of life support technology in perinatology and neo-natal intensive care,mortality of preterm infants has been reduced.However,the problems caused by the brain damage have been attracting more and more attention.The long-term outcome of prematures depends on their nervous system sequelae among the total complications.Preterm infants'brain damage mainly includes intravent-ricular hemorrhage(IVH)and periventricular leukomalacia(PVL).IVH and its complications are the main causes of early death,mental and physical developmental disorder of neonatals.Thus,the early diagnosis of brain dam-age,especially PVL,has become a serious problem that we are going to face.The scholars in or aboard hao payed close attention to these markers,such as MBP、S100B、ACT A、NF-L、NGB、MMP、IL-6、IL-10、IL-1 1 、NSE.The paper reviews these biological markers.