Early-noninvasive measurements about endothelial function in obese children
10.3760/cma.j.issn.1673-4408.2016.03.015
- VernacularTitle:肥胖儿童内皮功能紊乱早期无创评价方法
- Author:
Kana WANG
;
Chunlin WANG
- Publication Type:Journal Article
- Keywords:
Children;
Obesity;
Endothelial function;
Early-noninvasive measurement
- From:
International Journal of Pediatrics
2016;43(3):222-225
- CountryChina
- Language:Chinese
-
Abstract:
Along with the high prevalence of obesity in children and adolescents,obesity can lead to im-paired glucose tolerance,dyslipidemia,elevation of blood pressure,the risk of metabolic syndrome,diabetes,and cardiovascular and cerebrovascular diseases gradually increases.As end-event cardiovascular disease(CVD)is hardly present in childhood,there is a critical need for early markers to assess,predict,and treat the children who are vulnerable to developing CVD.For mitigating the incidence of future CVD through early detection and pre-vention programs,this paper reviews the relationship between endothelial dysfunction and immunologic dysfunc-tion,chronic inflammation,oxidative stress,insulin resistance.And it also provides a critical overview on early-noninvasive measurements about endothelial function in obese children.
