Evaluation on ovarian function after hysterectomy by detection of serum anti-Mullerian hormone levels
10.13481/j.1671-587x.20140437
- VernacularTitle:抗苗勒氏管激素检测对子宫切除术后患者卵巢功能的评价
- Author:
Haiying WANG
;
Jieling LIANG
;
Yanling BI
;
Renli ZHANG
;
Huaiqin LUO
;
Zhoumei JIANG
;
Anmin WEN
- Publication Type:Journal Article
- Keywords:
anti-Mullerian hormone;
hysterectomy;
ovarian function
- From:
Journal of Jilin University(Medicine Edition)
2014;(4):875-879
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of the new ovarian function marker serum anti-Mullerian hormone (AMH)and to clarify the effect of hysterectomy on the ovarian function of the younger women.Methods The serum AMH,follicle stimulating hormone (FSH)and luteinizing hormone (LH)levels in 35 women suffered uterus benign lesion aged 36-45 years and 35 women suffered hysteromyoma without operation were measured at different time.And the ovarian arterial blood flow resistance index (RI ) was measured by Doppler ultrasound. Results Compred with before operation, the serum AMH levels of the patients in hysterectomy group 2 d and 3 months after operation were significantly decreased (P<0.05 or P<0.01).Compared with control group,the serum AMH levels of the patients in hysterectomy group 2 d and 3 months after operation were also decreased (P<0.05).The ovarian arterial blood flow RI of the patients in hysterectomy group 1 and 3 months after operation were increased compared with control group (P<0.05).There were no significant differences in the serum FSH and LH levels in each group between different time points (P>0.05).Conclusion Hysterectomy can affect the ovarian function,and the serum AMH level 3 months after operation is decreased and the ovarian arterial blood flow RI is increased.AMH is superior to FSH or LH in evaluating the changes of ovarian function.