Development of a new kind of radioactive stent for the treatment of pancreatic and bile duct tumor
10.3760/cma.j.issn.1007-5232.2015.10.008
- VernacularTitle:一种治疗胰胆管恶性肿瘤的新型放射性支架的可行性研究
- Author:
Lizhou LIN
;
Xinjian WAN
- Publication Type:Journal Article
- Keywords:
Bile duct neoplasms;
Iodine-125;
Silica gel;
Stents
- From:
Chinese Journal of Digestive Endoscopy
2015;32(10):678-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a new silicone coating iodine-125 (s-125I) radioactive stent, and to compare it with the traditional titanium coating iodine-125 (t-125I) radioactive stent.Methods Medical silicone solution was mixed with 125I solution, evenly applied to specific locations of stents to make the silicone-coated 125I stents.The total radioactivity of 125I solution was 24mCi, by which 20 silicone-coated 125I stents were made.A total of 20 traditional titanium stents of the same radioactivity were collected, and the utilization rate of the radionuclides of the two types of stents were compared.Results With the same amount of radioactivity, the s-125 I stent showed a higher utilization rate of nuclide [91.2％ (21 878/24 000) VS 50.1％ (12 031/24 000)] (P ＜ 0.05).Conclusion The s-125I stent has a high utilization rate of nuclide,which can save the cost and energy largely.However, the application of the s-125I stent still needs further research.
