Clinical Randomized Controlled Research of Compound Qinbudan Recipe in Treating Multi-drug Resistant Pulmonary Tuberculosis of Deficiency of Both Qi and Yin
10.13359/j.cnki.gzxbtcm.2015.01.003
- VernacularTitle:复方芩部丹方治疗气阴亏虚型耐多药肺结核的随机对照研究
- Author:
Chenghua LU
;
Huiyong ZHANG
- Publication Type:Journal Article
- Keywords:
Multi-drug resistant pulmonary tuberculosis/TCD therapy;
Deficiency of both qi and yin;
Compound Qinbudan recipe/therapeutic use
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2015;(1):10-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of the compound Qinbudan recipe in treating multi-drug resistant pulmonary tuberculosis (MDR-PTB) of deficiency of both qi and yin. Methods A randomized controlled trial was carried out in 72 MDR-PTB cases, and the patients were divided into treatment group and control group, 36 cases in each group. The treatment group was treated with the compound Qinbudan recipe while the control group was treated with Feitai capsules. After treatment for 3 months, the therapeutic effect, scores of traditional Chinese medical syndromes, and adverse reactions were compared in the two groups. Results ( 1) After treatment for 3 months, the total effective rate of the treatment group was 82.86%, and that of the control group was 25.81%, the difference being significant (P <0.01) . (2) After treatment for 3 months, the total scores of traditional Chinese medical syndromes of the treatment group were lower than those of the control group, and the difference was significant ( P <0.05) . ( 3) At the end of the treatment course, the treatment group showed better effect on relieving shortness of breath, night sweating, spontaneous perspiration, cough with sputum than the control group ( P<0.05 or P <0.01) . The two groups had similar effect on relieving cough, dry throat, tidal fever, and emaciation ( P >0.05) . ( 4) Blood routine examination and hepatorenal function showed no disorders during the treatment. Gastrointestinal disturbance was not found either. Conclusion The compound Qinbudan recipe is effective in treating multi-drug resistant pulmonary tuberculosis of deficiency of both qi and yin, and has better effect on relieving shortness of breath, night sweating, spontaneous perspiration and cough with phlegm than Feitai capsules .
