Clinical observation of tramadol and sufentanil for postoperative analgesia after upper-abdominal surger-ies:a prospective study
- VernacularTitle:曲马多复合舒芬太尼用于上腹部手术后镇痛的多中心临床研究
- Author:
Guangmin ZHU
;
Ming XIA
;
Xiaoliang JIN
;
Yuhong LI
;
Jianguo XU
- Publication Type:Journal Article
- Keywords:
Tramadol;
Sufentanil;
Postoperative analgesia;
Upper-abdominal surgery
- From:
The Journal of Clinical Anesthesiology
2015;(12):1199-1201
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of tramadol combined with sufentanil on postop-erative analgesia in patients received upper-abdominal surgery.Methods One hundred and fifty pa-tients scheduled for selective upper-abdominal operation were randomly divided into five groups (n=30 each):Tramadol group (T);large dose sufentanil combined small dose tramadol group (TS1 );balanced tramadol and sufentani group (TS2 );small dose sufentanil combied large dose tramadol group (TS3);sufentanil group (S).Postoprative VAS scores were recorded respectively at 1,4,8, 12,24,36,48 h when be in quiet and turning 90 degree,Ramsay sedation score,analgesia pump pressing times and side effects were also recorded.Results VAS scores in group TS2,group TS3 and group S at each time point both be in quiet and turning 90 degree were significantly lower than that of group T and group TS1 (P <0.05).Group S sedation score significantly higher than group T (P <0.05).No significant difference in other groups.Conclusion Balanced tramadol and sufentanil group has best analgesic effect and least side effects.With the increasing doses of sufentanil,its analgesic effect was not obvious enhancement.