Advances in drug treatment of acromegaly
- VernacularTitle:肢端肥大症的药物治疗进展
- Author:
Liang ZHOU
;
Yi ZHANG
- Publication Type:Journal Article
- Keywords:
acromegaly;
pituitary adenoma;
insulin-like growth factor 1;
drug therapy;
somatostatin analogues
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):185-188
- CountryChina
- Language:Chinese
-
Abstract:
Acromegaly is mostly caused by a pituitary adenoma secreting growth hormone ( GH ) , which leads to a wide range of endocrine morbidities, with an insidious onset and slow progression.A long-term overproduction of GH results in elevated insulin-like growth factor-1 ( IGF-1 ) level, which in turn, would cause target organ damage and an increased risk for mortality and decreased quality of life.Herein, the literature regarding the progress of drug therapy for acromegaly in recent five years is reviewed.
