The effect of intravenous lidocaine on postoperative pain and acute rehabilitation after laparoscopic hys-terectomy
- VernacularTitle:静脉输注利多卡因对腹腔镜全子宫切除术后疼痛及早期康复的影响
- Author:
Juan ZHU
;
Fengzhen YAO
;
Rong ZOU
- Publication Type:Journal Article
- Keywords:
Lidocaine;
Intravenous infusion;
Laparoscopic hysterectomy;
Postoperative pain;
Acute rehabilitation
- From:
The Journal of Clinical Anesthesiology
2015;(12):1162-1164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of intravenous lidocaine on postoperative pain and acute rehabilitation after laparoscopic hysterectomy.Methods Ninety-six patients scheduled for lapa-roscopic hysterectomy under general anesthesia were randomized into 2 groups (n = 48 ).In test group,lidocaine 1.5 mg/kg was administered at induction,then with a continously infusing rate of 2 mg·kg-1 ·h-1 until the end of surgery.In control group,saline was instead.Record the resting and coughing pain scores at 6,12,24 and 48 h after surgery,morphine consumption during the first 48 h, time to first flatus,6 min walk test (6MWT)result,and side effects such as dizzy,nausea and vomi-ting.Results Resting VAS scores at 6,12 and 24 h postoperatively were lower in test group than in control group (P <0.05).Coughing VAS scores in test group were lower than in control group at all time points (P <0.05).The morphine consumption was lower in test group than in control group (P<0.05).Time to first flatus was earlier in test group than in control group (P <0.05 ).6MWT at day 4 and 5 were significantly enhanced in test group (P <0.05 ).Conclusion Intravenous lidocaine can reduce postoperative pain scores and morphine consumption,as well as improve early rehabilita-tion after laparoscopic hysterectomy.
