Preventive effect of Unaccompanied Ginseng decoction joint Xuanfu Daizhe decoction on complications in gastric cancer patients with post-operative adjuvant chemotherapy
- VernacularTitle:独参汤联合旋覆代赭汤在胃癌术后辅助化疗急性并发症预防中的作用
- Author:
Jinke KANG
;
Zhiqiang WANG
;
Mi SHEN
;
Mingjie MA
- Publication Type:Journal Article
- Keywords:
Unaccompanied Ginseng decoction;
Xuanfu Daizhe decoction;
gastric cancer;
adjuvant chemotherapy;
complications
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):58-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Unaccompanied Ginseng decoction joint Xuanfu Daizhe decoction on complications in patients with gastric cancer adjuvant chemotherapy, and select the best method to reduce the incidence of complications.Methods 80 patients of gastric cancer with postoperative adjuvant chemotherapy from May 2010 to May 2015 were divided into two groups, 40 cases in each group.The control group received Western medicine treatment and observation group received Unaccompanied Ginseng decoction joint Xuanfu Daizhe decoction , with a consecutive of one week.The clinical efficacy, adverse reactions and quality of life were compared between two groups.Results There was no significant difference in total efficacy between observation group and control group(77.5% vs.75.0%; χ2 =0.069,P>0.05).The KPS score, symptom and physical sign score, alanine aminotransferase, serum creatinine and systolic pressure in observation group post-treatment improved more than those in control group ( P<0.05).The adverse reaction rates of thrombocytopenia and myelosuppression in observation group was significantly lower than that in control group , respectively(P<0.05).Conclusion Unaccompanied Ginseng decoction joint Xuanfu Daizhe decoction could decrease the complications in gastric cancer patients with postoperative adjuvant chemotherapy.
