Shuxuening injection combined with deproteinized extract of calf blood on serum IGF-1, IL-1 and ICAM-1 in patients with cerebral infarction recovery stage
- VernacularTitle:舒血宁注射液联合小牛血去蛋白提取物对脑梗死恢复期患者血清IGF-1、IL-1及ICAM-1水平影响研究
- Author:
Hongwei REN
;
Liyu MAO
;
Hua QIAN
- Publication Type:Journal Article
- Keywords:
Shuxuening injection;
deproteinized extract of calf blood;
erebral infarction recovery stage;
insulin-like growth factor-1;
interleukin-1;
intercellular adhesion molecule-1
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):133-135
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate Shuxuening injection combined with deproteinized extract of calf blood on serum IGF-1, IL-1 and ICAM-1 level in patients with cerebral infarction recovery stage.Methods 120 patients with cerebral infarction were collected.According to the different drug treatment, 60 cases in each group were given corresponding drug treatment, on the basis of control group, the calf blood extract injection was given in experimental group.After the end of treatment, all patients blood rheology, IGF-1, IL-1 and ICAM-1 levels were tested.Results Compared with control group, the indexes of the patients in experimental group improved more significantly, whole blood viscosity, red blood cell pressure volume, platelet aggregation rate decreased significantly(P<0.05); serum IGF-1 levels in experimental group decreased significantly(P<0.05).The levels of serum IL-1, ICAM-1 in experimental group decreased significantly(P<0.05).Conclusion Shuxuening injection combined with deproteinized extract of calf blood can significantly reduce serum IGF-1, IL-1 and ICAM-1 levels in patients with cerebral infarction recovery stage, improve blood flow, reduce blood viscosity.
