Effect of Erigeron breviscapus oral liquid on peripheral blood CRP and MMP-9 in patients with acute coronary syndrome
- VernacularTitle:灯盏细辛口服液对急性冠状动脉综合征患者外周血CRP与MMP-9影响研究
- Author:
Ouhuan DAI
;
Xuejun ZHANG
;
Yan LIN
- Publication Type:Journal Article
- Keywords:
Erigeron breviscapus oral liquid;
acute coronary syndrome;
C reactive protein;
matrix metalloproteinase 9
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):136-138
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse effect of Erigeron breviscapus oral liquid on peripheral blood CRP and MMP-9 in patients with acute coronary syndrome.Methods 56 patients who were diagnosed with acute coronary syndrome were collected.All patients were randomly divided into experimental group and control group, 28 cases in each group.Patients in control group received conventional treatment with western medicine, patients in experimental group were given Erigeron breviscapus oral liquid of oral treatment on the basis of control group treatment, after the treatment, the serum levels of CRP,MMP-9 and clinical curative effect were detected in all patients.Results Compared with before treatment, the levels of CPR and MMP-9 in two groups decreased after the treatment(P<0.05); Compared with control group,the serum level of CRP was lower in experimental group(P<0.05); the serum level of MMP-9 was lower in experimental group(P<0.05);the total effective rate was higher in experimental group(χ2 =4.08,P<0.05).Conclusion Erigeron breviscapus oral liquid can significantly reduce the serum levels of CRP and MMP-9 in patients with acute coronary syndrome,improve clinical therapeutic effect.
