Clinical analysis of children with severe hand, foot and mouth disease
10.3760/cma.j.issn.1673-4904.2015.10.001
- VernacularTitle:重症手足口病患儿临床分析
- Author:
Qingfeng BAI
;
Fei LIU
;
Bo BAI
- Publication Type:Journal Article
- Keywords:
Hand;
foot and mouth disease;
Enterovirus infections;
Child
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(10):703-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical feature and the treatment of severe hand, foot and mouth disease (HFMD), and provide the basis for control of the disease. Methods The clinical data of 60 children with severe HFMD were retrospectively analyzed. Results All the 60 cases appeared fever and the erythra in hand, foot, mouth and gluteal region. Part of the children appeared jumping, body shaking, poor spirit and/or sleepiness. Some children appeared convulsion, and neurogenic pulmonary edema, pulmonary hemorrhage, cardiorespiratory failure happened in 2 critical severe cases. The children were given the comprehensive treatment including ribavirin, mannitol, human immunoglobulin and methylprednisolone. Forty-three cases were cured, 15 cases were improved, and 2 cases died. Conclusions Severe HFMD children usually appear critical condition. Early detection of critical signs and correct and effective clinical treatment can promote children's recovery and reduce the mortality rate.
