Exercise intensity exerts a two-way regulatory role in the immune response
10.3969/j.issn.2095-4344.2015.46.025
- VernacularTitle:运动强度对免疫反应可起到双向调控的影响效应
- Author:
Xue YI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2015;(46):7517-7522
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND:Studies have shown that high-intensity exercise has immunosuppressive effect, while low- and medium-intensity exercises have anti-inflammatory effect, both of which offer protection against many chronic diseases. OBJECTIVE: To study the relationship between immune system and exercise so as to explore the relevant mechanism underlying immunosuppressive and anti-inflammatory effects. METHODS:CNKI, Wanfang, and PubMed databases were retrieved for articles related to exercise immunology published from January 1990 to April 2015. Relevant mechanisms of action and research prospects were analyzed and expected. RESULTS AND CONCLUSION: Sixty articles related to sports and immune were included. High-intensity exercise has been proved to have a inhibitory effect on the immune function, and theories about immunosuppressive effect after high-intensity exercise is elementarily systemized. How to reduce and avoid immunosuppression impact of high-intensity exercise is stil worth exploring. Anti-inflammatory effect of low- and medium-intensity exercises is becoming more and more popular. Especialy, the endocrine effects of the skeletal muscle and the two-way regulatory role of interleukin-6 in the effects of different intensity exercise on the immune response are worthy of further exploration.
