Effect of abnormality Y chromosome and sperm quality on the result of insisted reproductive techniques
10.3969/j.issn.1006-5725.2016.05.013
- VernacularTitle:不育男性Y染色体长度异常的精液质量
- Author:
Wei XIE
;
Wen QIN
;
Dinggan MO
;
Meijia CHEN
;
Futong LV
;
Aipin QIN
- Publication Type:Journal Article
- Keywords:
Assisted reproductive technique;
Y chromosome;
Semen analysis;
Embryo structures;
Pregnancy outcome
- From:
The Journal of Practical Medicine
2016;32(5):727-730
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of abnormality Y chromosome and sperm quality on the clinical result of insisted reproductive technique (ART). Methods We retrospectively analyzed the effect of ab-normality Y chromosome and sperm quality on embryo quality/result of pregnancy of patients undergoing ART. In-fertile men with normality Y chromosome (n=436) and with abnormality Y chromosome (n =146) from Jan 2010 to Dec 2010 were enrolled in this study. The infertile men were divided into four groups: the normality Y chromo-some plus teratozoospermia group , the normality Y chromosome plus normal sperm quality group , the abnormality Y chromosome plus teratozoospermia group, the abnormality Y chromosome plus normal sperm quality group. Embryo quality and the results of clinic pregnancy outcome were analyzed among the four groups. Results Fertilization rate of the four groups was 73.4%, 69.0%, 70.9% and 68%, respectively (P < 0.05). No significant differences were found in thecleavage rate, optimal embryo rate and pregnancy outcome among the four groups. Conclusions Both abnormality Y chromosome length and teratozoospermia may be affect the fertility rate of the infertile men undergoing IVF/ICSI.
