Xiaoqinglong decoction combined with standard treatment for acute exacerbation of chronic obstructive pulmonary disease
10.3760/cma.j.issn.1673-4246.2016.04.009
- VernacularTitle:小青龙汤加味结合西医常规疗法治疗慢性阻塞性肺病急性加重临床研究
- Author:
Wenlian ZHENG
;
Jinhuan WANG
;
Yanlei GE
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
Disease progression;
Xiao Qing Long Tang;
Forced expiratory volume;
Oxygen;
Partial pressure;
Traditional and western medicine therapy
- From:
International Journal of Traditional Chinese Medicine
2016;38(4):319-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of Xiaoqinglong decoction combined with standard treatment for acute exacerbation of chronic obstructive pulmonary disease (COPD).Methods A total of 60 patients with acute exacerbation of COPD were enrolled and randomly divided into a standard treatment group and a combined treatment group, 30 in each group. The standard treatment group received standard therapy and the combined treatment group receivedXiao Qing Long decoction combined with standard treatment. The forced vital capacity (FVC), forced expiratory volume in first second (FEV1), FEV1/FVC were detected using a pulmonary function tester. The partial pressure of arterial oxygen (PaO2), carbon dioxide (PaCO2) were evaluated.Results After the treatment, the FVC (1.94 ± 0.26 Lvs. 1.55 ± 0.33 L;t=-2.201, P<0.05), FEV1 (1.34 ± 0.24 Lvs. 0.99 ± 0.25 L;t=-6.004,P<0.05), and PaO2 (86.12 ± 13.26 mmHgvs. 80.02 ± 12.75 mmHg;t=-14.158,P<0.05) in the combined treatment group were significantly higher than those in the standard treatment group. The total effective rate in the combined treatment group was significantly higher than that in the standard treatment group (86.7%vs.70.0%;χ2=2.095,P=0.036).Conclusions Xiaoqinglong decoction combined with standard treatment can improve symptom, sign, arterial blood gas and the pulmonary function in patients with acute exacerbation of COPD, and its efficiency is superior to standard therapy alone.
