Distributions of sIgE and tIgE in patents with allergic diseases in Guangdong
10.3969/j.issn.1006-5725.2016.04.016
- VernacularTitle:广东地区过敏疾病患者常见变应原sIgE和tIgE分布规律
- Author:
Peiyan ZHENG
;
Huimin HUANG
;
Nili WEI
;
Wenting LUO
;
Baoqing SUN
- Publication Type:Journal Article
- Keywords:
Allergens;
Total IgE;
Specific IgE
- From:
The Journal of Practical Medicine
2016;32(4):562-565
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the types and distributions of allergens, and the responsiveness to these allergens SIgE and tIgE as related to allergic disorders in patients with allergies in Guangdong. Methods Serum samples were obtained from patients with allergic disorders (n = 7 144) who visited our hospital between 2009 and 2014. The sera were subjected to analysis of 15 common allergens. Results The positive rates of sIgE and tIgE were 62.4%and 54.6%, respectively. Dermatophagoides pteronyssinus(Der p) had the highest prevalence of aeroallergen-specific IgE and milk the highest prevalence of food allergen-specific IgE. Other aeroallergens and food allergens produced mild responses except Der p and Der f. The sensitization peak of Der p and Der f appeared at the age of 10 to 12 years. The sensitization peak of milk appeared at the age of less than 3 years and that of eggs did at the aged of 4 to 6 years. The averaged tIgE positive rate went up with the increase in the number of allergen sensitization. Conclusion Der p, Der f, milk and eggs are major sensitizers responsible for common allergic disorders in Guangdong. Knowledge concerning allergen characteristics at various age groups may be helpful for early diagnosis and intervention for allergies.
