Effect of various anaesthesia depth on the sublingual microcirculation

VernacularTitle:不同麻醉深度对舌下微循环的影响
Author: Zhihui LIU ; Guolin WANG ; Peibo LI ; Keliang XIE ; Lingling LIU ; Yonghao YU
Publication Type:Journal Article
Keywords: microcirculation; tongue; stress; depth of anesthesia; bispectral index (BIS); sidestream dark-field technique
From: Tianjin Medical Journal 2015;(12):1447-1449
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of different depth of anesthesia on sublingual microcirculation. Meth?ods ASA gradeⅠ-Ⅱpatients (n=20) were scheduled for elective thyroid surgery and included in the prospective observa?tional study. Midazolam 0.05 mg·kg, sufentanil 0.3μg·kg-1 and rocuronium 0.6 mg·kg-1 were administrated intravenously to induce anesthesia which was then maintained by continuous intravenous infusion of propofol. Target medication concentra?tion increased 0.5 mg·L-1, regulated based on BIS. The patients underwent endotracheal intubation and mechanical ventila?tion. Sublingual microcirculations were evaluated by sidestream dark field (SDF) imaging at T1 (BIS baseline ), T2 (50 0.05). Conclusion When BIS value sit between 40 and 50, it can best inhibit stress response and attenuate the agitation of microcirculation.