Application of nucleic acid detection and antibody detection in HIV infection
10.3969/j.issn.1673-4130.2015.23.028
- VernacularTitle:核酸检测与抗体检测在HIV感染中的应用
- Author:
Haiyan HOU
;
Qingli YAN
;
Jing LIU
;
Chuncheng LIU
- Publication Type:Journal Article
- Keywords:
human immunodeficiency virus;
nucleic acid detection;
antibody detection
- From:
International Journal of Laboratory Medicine
2015;(23):3431-3432
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the accuracy of nucleic acid detection and antibody detection for diagnosing human immunode‐ficiency virus(HIV) infection .Methods Retrospectively analysed data of nucleic acid detection and antibody detection from 124 ca‐ses of patients diagnosed with HIV infection from 2005 to 2014 .The positive rates of the two methods were compared respectively in patients with early‐stage of HIV infection(76 cases) and patients with intermediate and advanced stage of HIV infection (48 ca‐ses) .Results In patients with early‐stage of HIV infectionn ,the positive rate of nucleic acid detection (94 .74% ) was higher than that of antibody detection (84 .21% );while in patients with intermediate and advanced stage of HIV infection ,the positive rate of antibody detection(97 .92% ) was higher than that of nucleic acid detection (81 .25% );both had statistically significant difference (P<0 .05) .Conclusion On the early stage of HIV infection ,the accuracy of nucleic acid detection is higher than that of antibody detection ;while on the intermediate and advanced stage of HIV infection ,antibody detection shows better accuracy .
