Observation of the effect of cinepazide maleate combined with Shuxuetong in the treatment of ischemic vertigo
10.3760/cma.j.issn.1008-6706.2015.24.016
- VernacularTitle:马来酸桂哌齐特联合疏血通治疗缺血性眩晕的疗效观察
- Author:
Yongxing SUN
- Publication Type:Journal Article
- Keywords:
Vertigo;
Brain ischemia;
Cinepazide maleate;
Shuxuetong
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(24):3729-3731
- CountryChina
- Language:Chinese
-
Abstract:
Objective To learn the effect of cinepazide maleate combined with Shuxuetong in the treatment of ischemic vertigo.Methods 1 81 cases with ischemic vertigo were randomly divided into the observation group (98 cases)and the control group(83 cases)by random number table method.The observation group was treated with cinepazide maleate combined with Shuxuetong,and the control group was treated with cinepazide maleate.The blood flow velocity of vertebral artery and basilar artery of the two groups were measured before and after a period of treat-ment.The therapeutic effects were evaluated after one course.Results The peak systolic velocity and end diastolic velocity of right vertebral artery,left vertebral artery and basilar artery of the two groups were higher than before treat-ment,the differences were statistically significant(t =1 1 .21 5,1 2.51 0,6.030,6.81 4,7.052,7.730,1 9.884,1 7.774, 1 0.954,1 9.320,1 9.483,1 9.1 98,all P <0.05).The peak systolic velocity and end diastolic velocity of right verte-bral artery,left vertebral artery and basilar artery in the observation group were significantly higher than those in the control group(t =5.577,6.404,3.601 ,1 0.028,1 0.1 94,8.1 65,all P <0.05).The total effective rate of the observa-tion group was 90.7%(78 /86),which was higher than 73.5%(61 /83)of the control group,and the difference was statistically significant(χ2 =9.500,P <0.05).The incidence rate of adverse reaction of observation group was 6.1 %(6 /98),that of control group was 7.2%(6 /83),the difference was not statistically significant(χ2 =0.089,P >0.05).Conclusion In the treatment of ischemic vertigo,cinepazide maleate combined with Shuxuetong has better curative effect and low incidence rate of drug adverse reaction.
