Observation of the effect of bisoprolol combined with simvastatin in the treatment of elderly patients with unstable angina

VernacularTitle:比索洛尔联合辛伐他汀治疗老年人不稳定型心绞痛的效果观察
Author: Lihai ZHENG ; Xiaoyun CHEN
Publication Type:Journal Article
Keywords: Angina,unstable; Bisoprolol; Simvastatin; Aged
From: Chinese Journal of Primary Medicine and Pharmacy 2015;(24):3767-3769
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of bisoprolol combined with simvastatin in the treatment of elderly patients with unstable angina pectoris.Methods 60 elderly patients with unstable angina pectoris were randomly divided into control group and study group according to the digital table method.The patients in the control group were treated with simvastatin,and the patients in the study group were treated with bisoprolol and simvastatin.The clinical therapeutic effect and adverse reactions of the two groups were compared.Results The total effective rate and the rate of ECG (86.67% and 80%)in the study group were significantly higher than those of the control group (76.67% and 46.67%)(χ2 =4.02,7.1 8,all P <0.05 ).The total incidence rate of adverse reactions (26.67%)in the study group had no significant difference compared with the control group (χ2 =0.08,P >0.05). Conclusion Bisoprolol combined with simvastatin had better clinical effect and small adverse reactions in the treat-ment of elderly patients with unstable angina.It was worthy of clinical use.