The clinical significance of monitoring of coagulation and fibrinolysis related indexes after hip replacement for preventing and diagnosing lower extremity deep venous thrombosis
10.3969/j.issn.1673-4130.2015.23.038
- VernacularTitle:髋关节置换后凝血纤溶相关指标监测对预防诊断下肢深静脉血栓的临床意义
- Author:
Qian ZHAN
- Publication Type:Journal Article
- Keywords:
lower extremity deep venous thrombosis;
hip joint;
D-dimer;
fibrinogen;
fibrin degradation products
- From:
International Journal of Laboratory Medicine
2015;(23):3453-3454
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of monitoring of D‐dimer ,fibrinogen and fibrin degradation products after hip replacement for diagnosing and preventing the lower extremity deep venous thrombosis .Methods A total of 66 cases of patients who carried out hip replacement from April 2013 to April 2015 in the department of orthopaedic in this hospital were se‐lected .Patients complicated with lower extremity deep venous thrombosis were enrolled into the observation group ,while patients without lower extremity deep venous thrombosis were enrolled into the control group .Levels of D‐dimer ,fibrinogen and fibrin deg‐radation products were strictly monitored after hip replacement and were comparatively analysed .Results There were no statisti‐cally significant differences in levels of fibrinogen and fibrin degradation products between the two groups (P>0 .05) ,while statisti‐cally significant difference was found in level of D‐dimer between the two groups(P<0 .05) .Conclusion The monitoring of D‐di‐mer ,fibrinogen and fibrin degradation products after hip replacement could have clinical significance for diagnosing and preventing lower extremity deep venous thrombosis .
