Transforming Process of Shikonin
10.3870/j.issn.1004-0781.2015.12.022
- VernacularTitle:左旋紫草素转化工艺
- Author:
Jian ZHOU
;
Ruixia GUO
;
Ruxing WANG
;
Guiqin ZHAO
- Publication Type:Journal Article
- Keywords:
Alkanna tinctoria pigment;
Shikonin;
Orthogonal design
- From:
Herald of Medicine
2015;34(12):1637-1639
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the optimal condition for transforming alkanna tinctoria pigment into shikonin. Methods Transformation rate of shikonin served as index. Transformation temperature, time, ratio of 2% NaOH to alkanna tinctoria pigment (v/w) was optimized. Results With ratio of 2% NaOH to alkanna tinctoria pigment being 4.5 mL·mg-1, temperature 35℃ and the reaction time 4 h, the transformation rate reached the highest, and the average transformation rate was 64.86%. Conclusion This method is easy and simple, and suitable for industrialized production.
