Association of osteoporosis with blood pressure variability in elderly patients with hypertension complicated by osteoporosis
10.3969/j.issn.1006-5725.2015.22.006
- VernacularTitle:老年骨质疏松合并高血压患者与血压变异性的相关性
- Author:
Yinfeng GAO
;
Da LIU
;
Wenli LUO
;
Jing WANG
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
The elderly;
Hypertension;
Blood pressure variability;
IL-6
- From:
The Journal of Practical Medicine
2015;31(22):3653-3656
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association of osteoporosis with blood pressure variability in elderly patients with hypertension complicated by osteoporosis, as well as its mechanisms. Methods A total of 189 elderly patients with hypertension were selected. According to the diagnostic criteria for osteoporosis, the patients were divided into three groups. 24-hour ambulatory blood pressure and IL-6 were detected in all the patients, and then compared among different groups. Results For the three group, there were statistical differences in levels of IL-6 and blood pressure variability (P < 0.05). Blood pressure variability was negatively correlated with BMD (P < 0.05). 3. IL-6 was positively related with blood pressure variability (P < 0.05), but had a negative correlation with BMD (P < 0.01). IL-6 had significant statistical differences among different sexes (P < 0.01). Conclusions Osteoporosis is closely associated with blood pressure variability in the elderly patients. IL-6 and blood pressure variability may play a synergistic role in the process of osteoporosis; and IL-6 may be a risk factor for postmenopausal osteoporosis in women.
