Some diseases caused by Parkin
10.3969/j.issn.1001-1978.2016.04.003
- VernacularTitle:Parkin相关疾病的研究进展
- Author:
Yina JIANG
;
Yuxia LOU
;
Zhao ZHANG
;
Naihong CHEN
- Publication Type:Journal Article
- Keywords:
Parkin;
ubiquitin;
protein substrates;
Parkinson′s disease;
cancer;
tumor suppressor;
leukemia
- From:
Chinese Pharmacological Bulletin
2016;32(4):455-458
- CountryChina
- Language:Chinese
-
Abstract:
Since Parkin was confirmed by the Japanese scholar to be associated with juvenile Parkinson′s disease, it has come to be the focus of the scholars and a lot of researches have been made on it. Apart from Parkinson′s disease, many other disea-ses have also been proved to be associated with the role of Parkin and its interaction with protein substrates, especially in various kinds of cancer diseases and leukemia. This paper focuses on the latest research about Parkin and its development in tumor diseases and leukemia.
