Related factors of obstructive sleep apnea sysdrome in type 2 diabetes patients
10.3969/j.issn.1006-5725.2016.03.019
- VernacularTitle:2型糖尿病患者阻塞性睡眠呼吸暂停综合征相关因素分析
- Author:
Min WANG
;
Min YI
;
Rongping CHEN
;
Rui YANG
;
Huapeng YU
;
Hong CHEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Obstructive sleep apnea syndrome;
Related factors
- From:
The Journal of Practical Medicine
2016;32(3):408-411
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the related factors of obstructive sleep apnea syndrome (OSAS) in type 2 diabetes mellitus (T2DM) patients. Methods 289 participants were enrolled and 254 people finished the whole process. Portable sleep monitor was used to detect the breath situation during sleep , and related factors were also analyzed. Finally , 183 subjects were diagnosed as OSAS and 71 subjects were not. Results 254 T2DM subjects were enrolled, with 108 males (59%) and 183 participants were diagnosed as OSAS (72%). OSAS group had a higher diabetic duration,body mass index, 2 h plasma glucose,fasting insulin, C peptide level, systolic blood pressure, triglyceride, low density lipoprotein cholesterol, and homocysteine levels(P<0.01). The prevalences of dyslipidemia , hyperuricemia , high blood pressure , non-alcoholic fatty liver disease and metabolic syndromein OSAS group were also higher than that in compared groups. Logistic regression analysis showed that body mass index, dyslipidemia and high homocysteine level were independent risk factors of OSAS. Conclusions The prevalence of OSAS in T2DM was higher. Blood glucose level , body mass index and multiple metabolic parameters in OSAS patients elevated significantly. Obesity and insulin resistance were major factors during the process of the disease.