Differences of Plasma NT-proBNP Level in Patients With Left Heart Failure Combining or not Combining Pulmonary Hypertension
10.3969/j.issn.1000-3614.2016.03.005
- VernacularTitle:合并或不合并肺动脉高压的左心衰竭患者血浆N末端B型利钠肽原水平的差异
- Author:
Binru SHEN
;
Yu ZHANG
;
Yan CUI
;
Lei LIU
- Publication Type:Journal Article
- Keywords:
Heart failure;
Hypertension,pulmonary;
NT-proBNP
- From:
Chinese Circulation Journal
2016;31(3):226-228
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the relationship between plasma levels of NT-proBNP and pulmonary hypertension in patients with left heart failure (LHF).
Methods: A total of 391 LHF patients were enrolled in our study, according to pulmonary arterial pressure, the patients were divided into 3 groups: Control group, the patients without pulmonary hypertension,n=102, Mild pulmonary hypertension group,n=94 and Moderate to severe pulmonary hypertension group,n=195. Plasma levels of NT-proBNP, left ventricular diameter (LVD), right ventricular diameter (RVD) and left ventricular ejection fraction (LVEF) were examined and compared among 3 groups.
Results: Plasma levels of NT-proBNP and RVD in Mild pulmonary hypertension group and Moderate to severe pulmonary hypertension group were higher than Control group, those indexes in Moderate to severe pulmonary hypertension group were higher than Mild pulmonary hypertension group,P<0.05-0.001. While LVD and LVEF were similar among 3 groups, P>0.05.
Conclusion: Plasma levels of NT-proBNP were increased in LHF patients combining pulmonary hypertension, the changing trend elevated with the increased pulmonary hypertension accordingly.
