Clinical Outcomes for Stent-thrombosis at Different Times in Patients After Drug-eluting Stent Implantation

VernacularTitle:药物洗脱支架置入术后不同时期发生支架内血栓患者临床预后的比较
Author: Li XU ; Lefeng WANG ; Xinchun YANG ; Dapeng ZHANG ; Hao SUN ; Hongshi WANG ; Yu LIU ; Weiming LI ; Zhuhua NI
Publication Type:Journal Article
Keywords: Stent,drug-eluting; Thrombosis formation; Follow-up study
From: Chinese Circulation Journal 2016;31(3):236-239
CountryChina
Language:Chinese
Abstract: Objective: To study the clinical outcomes of stent-thrombosis (ST) at different times in patients after drug-eluting stent (DES) implantation.
Methods: A total of 131 coronary angiography conifrmed ST patients in our hospital from 2005-01 to 2015-04 were studied. According to the time of ST occurrence, the patients were divided into 2 groups: Early ST group, ST occurred ≤30 days,n=42 and Late ST group, ST occurred >30 days,n=89. The in-hospital and follow-up information was collected; clinical outcomes were compared between 2 groups.
Results: The in-hospital MACE occurrence rate in Early ST group was higher than that in Late ST group (16.7% vs 4.5%),P=0.04. There were 123 patients survived to discharge and they were followed-up for the median of 38.00 (15.00, 62.00) months. Kaplan-Meier analysis estimated that the MACE-free survival was similar between 2 groups (41.9% vs 36.3%), P=0.43.
Conclusion: In-hospital MACE occurrence was higher in early ST patients, while the long term prognosis was similar between the early and late ST patients for whom with DES implantation.