Exploration of Plasma Levels of Catestatin in Patients With Different Blood Pressure and Metabolic Status
10.3969/j.issn.1000-3614.2016.03.013
- VernacularTitle:不同血压及代谢水平患者血浆儿茶酚抑素变化的探讨
- Author:
Juan JIANG
;
Ningling SUN
- Publication Type:Journal Article
- Keywords:
Hypertension;
Metabolic syndrome;
Catestatin;
Norepinephrine
- From:
Chinese Circulation Journal
2016;31(3):259-262
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze plasma levels of catestatin (CST) in patients with different blood pressure (BP) and metabolic status.
Methods: Our research included in 3 groups: Control group,n=60 subjects with normal BP from physical examination in our hospital; 131 patients with essential hypertension (EH) were divided into 2 groups: Isolated EH group,n=90 and MS (metabolic syndrome) group,n=41. Plasma levels of CST, norepinephrine (NE) were examined, the ratio of CST/NE was calculated, and those indexes were compared among different groups.
Results: Compared with Control group, plasma levels of CST and the ratios of CST/NE were decreased in Isolated EH and MS groups,P<0.05-0.01. As BP increasing, plasma levels of CST were gradually decreased; compared with Isolated EH group, plasma level of CST and CST/NE were reduced in MS group,P<0.05.
Conclusion: Plasma levels of CST and the ratio of CST/NE were obviously decreased in EH patients, CST was even lower in MS patients which implied that CST might be involved in the development of EH and MS.
