Performance of 18 F-FDG PET/CT in the diagnosis of recurrent and metastatic endometrial cancer
10.3760/cma.j.issn.2095-2848.2016.01.010
- VernacularTitle:18F-FDGPET／CT显像在子宫内膜癌术后复发及转移中的价值
- Author:
Dandan CHEN
;
Hubing WU
;
Quanshi WANG
;
Wenlan ZHOU
;
Hongsheng LI
;
Lijuan WANG
;
Ying TIAN
;
Ye DONG
- Publication Type:Journal Article
- Keywords:
Endometrial neoplasms;
Tomography,emission-computed;
Tomography,X-ray computed;
Deoxyglucose
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2016;(1):39-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of 18 F?FDG PET/CT in the diagnosis of recur?rent and metastatic endometrial cancer. Methods A total of 62 patients with endometrial cancer from October 2004 to February 2014 were retrospectively analyzed. The diagnostic efficiency of 18 F?FDG PET/CT for the de?tection of recurrent and metastatic endometrial cancer was evaluated based on the results of pathological biopsy or clinical follow?up. Results There were 28 endometrial cancer cases with recurrence and metastasis, 9 ca?ses with a second primary cancer and without recurrence and metastasis of endometrial carcinoma. PET/CT imaging had false positive findings in 3 cases, false negative findings in 2 cases. The overall sensitivity, speci?ficity and accuracy of PET/CT for detection of recurrence and metastatic endometrial carcinoma were 93.3%(28/30), 90.6%(29/32), 91.9%(57/62), respectively. The sensitivity and specificity of PET/CT for the diagnosis of vaginal stump recurrence, lymph node metastasis and distant metastasis were 9/10 and 98. 1%(51/52), 95.7%(22/23) and 92.3%(36/39), 15/18 and 95.5%(42/44), respectively. Conclusion 18F?FDG PET/CT is a useful diagnostic tool for the detection of recurrent and metastatic endometrial cancer and a second primary cancer.
