Effect of rivaroxaban on prevention from deep venous thrombosis after hip replacement surgery
- VernacularTitle:利伐沙班预防髋关节置换术后深静脉血栓的效果观察
- Author:
Jianchang LI
;
Chenhui MU
;
Yang GUO
- Publication Type:Journal Article
- Keywords:
rivaroxaban;
hip replacement surgery;
deep vein thrombosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):148-149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of rivaroxaban on prevention from deep venous thrombosis after hip replacement surgery .Methods 80 patients with lower limb parallel arthroplasty were randomly divided into observation group and control group from January 2014 to January 2015.40 cases in each group.Control group was given aspirin treatment, observation group was given rivaroxaban treatment, indicators changes were followed up and recorded.Results PT, APTT values of observation group one week after treatment were (35.79 ±2.16),(15.84 ±2.11) s, which were better than control group (45.64 ±2.12),(18.72 ±2.02) s (P<0.05).TT, D-dimer of observation group(13.48 ±2.10)s,(2.34 ±0.33)g/L after a week were better,than control group (16.38 ±1.79)s, (1.42 ±0.21)g/L (P<0.05) respectively.Conclusion Effect of rivaroxaban in prevent deep venous thrombosis after hip replacement surgery is exact without obvious adverses reaction, it is worthy of further research and application.
