Application of Spectral-domain Optical Coherence Tomography for Measuring Peripapillary Atrophy in Glaucoma
- VernacularTitle:利用频域光学相干断层扫描测量青光眼视盘旁萎缩区
- Author:
Xiaoli MA
;
Xianjie LIU
;
Yutong CHEN
;
Dandan LI
;
Hongwei ZHANG
;
Rui HUA
- Publication Type:Journal Article
- Keywords:
glaucoma;
peripapillary atrophy;
spectral domain-optical coherence tomography
- From:
Journal of China Medical University
2015;(12):1057-1060
- CountryChina
- Language:Chinese
-
Abstract:
Objective to measure peripapillary atrophy(PPA)in glaucoma with high-resolution spectral domain-optical coherence tomography (SD-OCt)and conventional color fundus photograph,and compare the consistency of the results between the two imaging methods. Methods A to-tal of 30 patients(54 eyes)with glaucoma from Department of Opthalmology,the First Hospital,China Medical University were prospectively includ-ed for the study. SD-OCt images and color fundus photographs taken through the region of PPA were qualitatively analyzed. the average width of β-PPA area in 6 reference lines centered optic nerve were measured using SD-OCt and color fundus photograph. Correlation and agreement between the two measuring methods were analyzed. Results the average width of β-PPA was 229.89±99.82 μm using color fundus photographs and 224.14±97.10 μm using SD-OCt,respectively. there was no significant difference(P = 0.280). the correlation coefficient was 0.825 between re-sults measured by SD-OCt and color fundus photographs for β-PPA area(P < 0.001),and agreement between the two methods was good(ICC=0.923,95% CI 0.870-0.954). Conclusion the correlation and consistency is good between SD-OCt and conventional color fundus photograph measuring β-PPA area. β-PPA area can be estimated with SD-OCt.