Effect of different concentrations of sevoflurane combined with propofol on CPR and complement in patients with laparoscopic hysterectomy
- VernacularTitle:不同浓度七氟烷联合丙泊酚对腹腔镜子宫切除术患者血清C反应蛋白以及补体变化的研究
- Author:
Xinhua HUANG
;
Yaqin ZHANG
;
Huili ZHU
- Publication Type:Journal Article
- Keywords:
sevoflurane;
propofol;
laparoscopic hysterectomy;
C reactive protein;
complement
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):61-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of different concentrations of sevoflurane combined with propofol on CPR and complement in patients with laparoscopic hysterectomy.Methods 80 patients with hysteromyoma were randomly divided into A group with 27 cases, B group with 27 cases and C group with 26 cases.3 groups of patients were underwent laparoscopic hysterectomy surgery, and preoperative anesthesia with different concentrations of sevoflurane, A group with 2.5% sevoflurane anesthesia, B group with 3% sevoflurane anesthesia, C group with 3.5%.The clinical efficacy, CRP, complement levels and adverse reactions were compared among 3 groups.Results Compared with A group, the Karnofsky score of group B and group C was higher(P<0.05), there was no significant difference in Karnofsky score between the two groups of B and C, and the level of CRP in 3 groups increased and C3 and C4 decreased(P<0.05).Compared with group A, the level of CPR in group B and C were lower(P<0.05), C4 and C3 were higher( P<0.05 ) .There was no significant difference in the incidence of adverse reactions among 3 groups.Conclusion 3% concentration of sevoflurane combined with propofol in the induction of anesthesia in laparoscopic hysterectomy has better anesthetic effect, and has little effect on the CRP and the complement of the body .
