Comparative research between hormone replacement therapy and self-prescribed Anshen pills for menopausal syndrome
- VernacularTitle:激素替代与自拟安神丸治疗更年期综合征的对照研究
- Author:
Qiuxia ZHANG
;
Qian YANG
;
Chuanying WU
- Publication Type:Journal Article
- Keywords:
self-prescribed Anshen pills;
hormone;
menopausal syndrome;
clinical effects
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):97-99
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of self-prescribed Anshen pills in the treatment of female patients with menopausal syndrome . Methods From August 2012 to September 2014, 100 female patients with menopausal syndrome in Tianjin Beichen District Chinese Medicine were randomly divided into control group (50 cases) and observation group (50 cases).The control group received tibolone orally, and the observation group received self-prescribed Anshen pills orally.All treated for 3 months.Modified Kupperman score, self-rating anxiety scale ( SAS) score, self-rating depression scale (SDS) score, Pittsburgh sleep quality index (PSQI) score, menopause-specific quality of life (MENQOL) score, the main clinical symptoms and hormone levels in serum were compared; the adverse reactions were recorded.Results Compared with control group post-treatment, hot flashes and perspiration, insominia improved greatly in observation group.The serum levels of luteinizing hormone ( LH ) in observation group was (28.04 ±3.37)IU/L, which was higher than (24.48 ±6.63)IU/L in control group.PSQI score in observation group was (6.57 ±1.23), which was lower than (8.18 ±1.70) in control group.The incidence of adverse reactions in observation group was 4.0%, which was lower than 18.0% in control group, and there were significant differences between two groups ( P<0.05 ) .Conclusion Self-prescribed Anshen pills is effective and safe for menopausal syndrome.
