Effect of low frequency electrical stimulation on hormone levels in the organs of Chinese tree shrew cadavers

VernacularTitle:低频电刺激对中国树鼩死亡后脏器中激素水平影响
Author: Farong YU ; Jing ZHANG ; Lirong GUO ; Wen YU ; Xiuzhen LIAN ; Mingren XIE ; Denglou LI ; Shishuang ZHANG
Publication Type:Journal Article
Keywords: Chinese tree shrews; Cadaver; Visceral organs; Hormone; C-fos expression; Electrical stimulation
From: Acta Laboratorium Animalis Scientia Sinica 2015;(6):578-581
CountryChina
Language:Chinese
Abstract: Objective To study the effect of low frequency electrical stimulation on hormone levels in organs of Chinese tree shrews after death.Methods Giving Chinese tree shrews low frequency electrical stimulation.At 0 h, 3 h, 6 h, 12 h, 18 h, 24 h, 36 h and 72 h after death, the thyroid, liver, spleen were taken,and the levels of endothelin (ET), atrial natriuretic factor( ANF) , thromboxane ( TX) were determined by RIA method.At 0 h after death, midbrain ventral tegmental area ( VTA) of Chinese tree shrews was taken to detect the c-fos expression.Results After electrical stimula-tion, ET, ANF, TX levels in the cadaver organs and VTA c-fos expression of Chinese tree shrews were significantly in-creased than in the control group.The contents were decreasing with the time after death.Conclusions Low frequency e-lectrical stimulation can induce the synthesis and release of hormones in organs and c-fos expression in brain tissue of Chi-nese tree shrews.