Effect of octreotide combined with ulinastatin on serum lipase, CRP and clinical efficacy in patients with acute pancreatitis
- VernacularTitle:奥曲肽联合乌司他丁对急性胰腺炎患者血清脂肪酶、CRP及临床疗效影响研究
- Author:
Bing SUN
;
Futian SHI
;
Yongqian MENG
- Publication Type:Journal Article
- Keywords:
octreotide;
ulinastatin;
acute pancreatitis;
lipase;
CRP
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):122-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study effect of octreotide combined with ulinastatin on serum lipase, CRP and clinical efficacy in patients with acute pancreatitis.Methods 60 cases with acute pancreatitis were selected and divided into 2 groups.30 cases in the control group were treated with ulinastatin.30 cases in the experiment group were treated on the base of the control group by octreotide.Clinical effects, lipase and CRP were compared after 1 weeks treatment.Results Compared with the control group after treatment, the serum lipase, CRP level was lower in the experiment group (P<0.05), and the clinical total effective rate was significantly higher in the experiment group than in the control group ( P<0.05 ) . Conclusion Octreotide combined with ulinastatin has good clinical curative effect on acute pancreatitis.It is speculated that the mechanism may be related to the decreasing of serum lipase and CRP level in patients.
