Research progress of neoadjuvant therapy for borderline resectable pancreatic cancer
10.16571/j.cnki.1008-8199.2015.12.024
- VernacularTitle:可能切除的胰腺癌行新辅助治疗的研究进展
- Author:
Daojun ZHU
;
Xinbo WANG
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer;
Neoadjuvant therapy;
Chemotherapy
- From:
Journal of Medical Postgraduates
2015;(12):1341-1344
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is known as one of the most fatal malignant diseases in digestive system.Approximately 15%-20%of patients are deemed resectable at the time of diagnosis.Neoadjuvant therapy to the borderline resectable pancreatic cancer ( BRPC) has been challenged to achieve down-staging of cancer, to avoid unnecessary major operation if the pancreatic cancer progres-ses and distant metastasis develops during preoperative treatment.However, there are some controversial issues influencing the clinical decision of surgeon in managing BRPC.This manuscript reviews the current controversial issues in managing BRPC in order to enhance proper understanding for the current status and potential role of neoadjuvant therapy in managing BRPC.
