Notch Signaling Pathway with the Polarization of Macrophages
10.16571/j.cnki.1008-8199.2015.12.019
- VernacularTitle:Notch 信号通路调节巨噬细胞极化研究进展
- Author:
Hongrong LI
;
Ying SUN
;
Chengcheng CHANG
;
Zhenhua JIA
- Publication Type:Journal Article
- Keywords:
Notch;
Conduction;
Macrophage;
Polarization;
Atherosclerosis
- From:
Journal of Medical Postgraduates
2015;(12):1316-1321
- CountryChina
- Language:Chinese
-
Abstract:
Macrophages play an important role in the pathogenesis of many diseases because of its plasticity and diversity.The Notch signaling pathway is a key regulator of the biological function of macrophage and has a complex network connection with many other signaling pathways.This paper reviews the conduction of Notch signaling pathway and its regulation on the polarization of macro-phages.