Research progress of protective effect of GLP-1 receptor agonist on vascular endothelial cell
10.3969/j.issn.1006-6187.2015.12.019
- VernacularTitle:胰升血糖素样肽-1受体激动剂对血管内皮细胞保护作用的研究进展
- Author:
Sujie KE
;
Yaoming XUE
- Publication Type:Journal Article
- Keywords:
Glucagon-like peptide-1(GLP-1);
Vascular endothelial cell;
Diabetes mellitus,type 2
- From:
Chinese Journal of Diabetes
2015;(12):1127-1130
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] Type 2 diabetic patients often have risk factors such as hyperglycaemia ,dyslipidaemia , hypertension ,obesity and insulin resistance ,which increase the risks of vascular endothelial dysfunction and cardiovascular events. GLP-1 analogue and its receptor agonist ,is a novel therapy on diabetes targeting at incretin ,which can effectively control blood glucose and improve vascular endothelial dysfunction. Here we summarize the protective effect of GLP-1 analogue and its receptor agonist on vascular endothelial cell.