Gut hormones in obesity and diabetes
10.3969/j.issn.1006-6187.2015.12.023
- VernacularTitle:肠道激素与肥胖和糖尿病
- Author:
Wenying YANG
- Publication Type:Journal Article
- Keywords:
Gut hormones;
Diabetes mellitus,type 2;
Obesity
- From:
Chinese Journal of Diabetes
2015;(12):1142-1148
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] Pathophysiological mechanisms of obesity and type 2 diabetes is complex . In recent years ,data has showed that guthormone in obesity and T 2DM patients has changed ,and guthormones such as GLP-1 ,GIP ,PYY ,CCK and ghrelin are strongly related to the development of obesity and diabetes , resulting in a series of metabolic disorders ,this may be one of causes of the development of obesity and T2DM. In recent years ,the guthormone-based treatments or therapies associated with guthormone have became one of the hot topics in the diabetes research. Currently ,some guthormone-based treatment shave been used in clinical treatment of diabetes. This paper is a literature review on the history of gut hormones ,and how it affect the development of diabetes and obesity ,as well as aspects of clinical practice.
