Etiologies of 224 patients with fever of unknown origin
10.3969/j.issn.1671-9638.2015.12.006
- VernacularTitle:224例不明原因发热患者病因分析
- Author:
Zengwei LIANG
;
Xushuo XIE
;
Xiaohan HUANG
;
Ling YANG
;
Yingyan OU
;
Wenting ZENG
- Publication Type:Journal Article
- Keywords:
fever of unknown origin;
infectious disease;
connective tissue disease;
tumor;
clinical feature
- From:
Chinese Journal of Infection Control
2015;(12):814-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the etiologies of fever of unknown origin(FUO)and methods for confirming di-agnosis in patients at a hospital,and provide reference for clinical diagnosis and treatment of FUO.Methods Pa-tients with FUO admitted to a hospital between January 2008 and July 2014 were performed clinical diagnosis with methods of serology,bacteriology,molecular biology,bone marrow aspiration,tissue biopsy,and diagnostic thera-py,the etiologies and final diagnosis of 224 patients were analyzed retrospectively.Results Of 224 FUO cases,189 (84.38%)eventually got confirmed diagnosis,35 (15.62%)were not confirmed.The percentage of infectious dis-eases,connective tissue diseases,malignant tumor,and other diseases were 50.45%,18.75%,9.82%,and 5.36%respectively.Among infectious diseases,the major pathogens were bacteria,followed by virus.The major connec-tive tissue diseases were systemic lupus erythematosus and polyarteritis nodosa;the main malignant tumor was he-matological tumor,lymphoma was the main form.Among 189 patients with confirmed diagnosis,30.16% and 24.34% were performed pathogenic and pathologic detection respectively,and 20.11% were performed the other (compre-hensive)methods.Conclusion Infectious diseases,connective tissue diseases,and tumor are major etiologies of FUO.
