Homology of carbapenem-resistant Klebsiella pneumoniae in an intensive care unit
10.3969/j.issn.1671-9638.2015.12.010
- VernacularTitle:重症监护病房耐碳青霉烯类肺炎克雷伯菌同源性分析
- Author:
Huiqiong PAN
;
Xuefeng YUAN
;
Min ZHOU
;
Xiaoling LI
;
Luchi LI
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
carbapenem-resistant Klebsiella pneumoniae;
homology;
intensive care unit;
healthcare-associated infection
- From:
Chinese Journal of Infection Control
2015;(12):827-829
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand antimicrobial resistance and homology of carbapenem-resistant Klebsiella pneumoniae (CRKP)from an intensive care unit (ICU).Methods 11 CRKP isolates from patients and environment of an ICU in a hospital were performed antimicrobial susceptibility testing,the homology of CRKP was analyzed by randomly amplified polymorphic DNA (RAPD)method.Results Of 11 CRKP isolates,8 were from patients,and 3 from environment,the main specimen was sputum(n =6,54.55%).Antimicrobial susceptibility testing results re-vealed that 10 (90.91%)CRKP isolates were resistant to ciprofloxacin;11 isolates were susceptible to compound sulfame-thoxazole,intermediate to imipenem,and resistant to other antimicrobial agents(100%).All 11 CRKP isolates had 3 bands,and were divided into two types:(typeⅠ,n=10;type Ⅱ,n=1).Conclusion Antimicrobial resistance of Kleb-siella pneumoniae in ICU is serious,CRKP isolated from ICU patients and environment are of the same clone. Cleaning,disinfection,and monitoring of ICU environment should be strengthened,which is helpful for reducing, timely warning of multidrug-resistant organisms,and reducing healthcare-associated infection.
