Influence on Pulmonary Function and Immune Function in Children with Capillary Bronchitis byRe-Du-NingInjection Combined with Acupoint Sticking
10.11842/wst.2015.10.026
- VernacularTitle:热毒宁联合穴位贴敷对毛细支气管炎儿童肺功能及免疫功能的影响＊
- Author:
Qiaohong ZHANG
- Publication Type:Journal Article
- Keywords:
Capillary bronchitis;
Re-Du-Ning injection;
immune function;
pulmonary function
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;(10):2099-2103
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to observe the influence on immune function in children with capillary bronchitis byRe-Du-Ning(RDN) injection combined with acupoint sticking, in order to explore the clinical application value of RDN injection combined with acupoint sticking. A total of 64 children with capillary bronchitis treated in the Henan Province Hospital of Traditional Chinese Medicine from October 2012 to August 2014 were randomly divided into two groups. In the control group, conventional treatment, including sputum excretion, oxygen therapy, cough-relieving and phlegm-dissolving, anti-inflammation, antifebrile, panting-relieving and atomization inhalation, was used. In the observation group, RDN injection combined with acupoint sticking of Ru-Yi Jin-Huang (RYJH) powder was used on the basis of treatment of the control group. Observations were made on the clinical therapeutic effects as well as the recovery condition of pulmonary function and immune function in both groups. The results showed that the asthmatic suffocating relieving time, asthmatic suffocating, cough, antifebrile, dry rale and wet rale disappearing time, hospitalization days of the observation group were less than those of the control group with significant inter-group difference (t = 4.346, 5.301, 4.445, 2.238, 4.116, 3.733, 3.681,P < 0.05). However, there were no significant differences in both groups (P > 0.05). There were no statistical differences on the pretreatment RR, VT, FRC, VPEF/VE, tPTEF/tE, Reff in both groups (P > 0.05);the posttreatment RR, VT, VPEF/VE, tPTEF/tE were obviously higher than those of the pretreatment; FRC and Reff were obviously decreased compared with those of the pretreatment (P < 0.05). The posttreatment RR, VT, VPEF/VE, tPTEF/tE in the observation group were higher than those of the control group; FRC and Reff were lower than those of the control group with significant difference (P > 0.05). There were no significant differences on the pretreatment T lymphocyte subsets, which included CD3+, CD4+ and CD8+ T lymphocyte (P > 0.05). The posttreatment CD3+ and CD4+ were higher than those of pretreatment; CD8+ was lower than that of pretreatment in both groups with significant difference (P < 0.05). In the observation group, the postreatment CD3+ and CD4+ were higher than those of the control group; CD8+ was lower than that of the control group with significant inter-group difference (P < 0.05). There were no significant differences on IgM, IgG, IgA, IgE and insulin-like growth factor 1 (IGF-1) before treatment in both groups (P > 0.05). The posttreatment IgG, IgA, IgM and IGF-1 were higher than those of the pretreatment; IgE was lower than that of the pretreatment with significant difference (P < 0.05). The posttreatment IgG, IgA, IgM and IGF-1 of the observation group were higher than those of the control group;IgE was lower than that of the control group with significant inter-group difference (P < 0.05). It was concluded that on the basis of conventional modern medicine treatment, the RDN injection combined with acupoint sticking can improve the clinical symptoms and pulmonary function, boost immune function in children with capillary bronchitis.
