New Research Ideas on Biomarkers of Syndrome of Phlegm-heat Obstructing the Lung in Children with Adenovirus Pneumonia

VernacularTitle:基于代谢组学的小儿腺病毒肺炎痰热闭肺证生物标志物研究思路＊
Author: Xintai WANG ; Lina DU ; Shouchuan WANG
Publication Type:Journal Article
Keywords: Adenovirus pneumonia; syndrome of phlegm-heat obstructing the lung; traditional Chinese medicine syndrome; metabonomics; biomarkers
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(10):2177-2180
CountryChina
Language:Chinese
Abstract: Study on the scientific essence of traditional Chinese medicine (TCM) syndrome is the key in TCM modernization. This paper showed new research ideas for TCM syndrome, which was based on the pediatric adenovirus pneumonia and its TCM treatment, metabonomics and its application in TCM syndrome research, in order to discuss its application value in the diagnosis and treatment of pediatric viral pneumonia. This method was mainly implemented through the metabonomics technology, which reflected TCM holism concept. The syndrome of phlegm-heat obstructing the lung, which was the most frequent syndrome in the pediatric viral pneumonia, was studied. Through the comparison with metabolites of healthy children, the biomarkers of syndrome of phlegm-heat obstructing the lung in pediatric viral pneumonia were identified.